A Clot Retriever Device for the Treatment of Acute Ischemic Stroke and Occlusions in Peripheral Vessels
A Clot Retriever Device for the Treatment of Acute Ischemic Stroke and Occlusions in Peripheral Vessels

CLOT-SPECIFIC
Micro-surface technology designed for a robust engagement with the clot's micro-structure

GENTLE AND SAFE
Polymer-based, non-traumatic to the vessel wall

FAST AND SIMPLE
“Over-the-Wire” technology designed for a first pass revascularization
Background
Stroke
- Stroke is the third-leading cause of death in the U.S., Canada, Europe, and Japan1
- The NIH estimates that stroke costs exceed $73 billion in U.S. healthcare expenditure per year1
- In the U.S. there are 795,000 new or recurrent strokes each year2

Estimated potential global market size of clot retriever devices for ischemic stroke4:
over $1 billion
Periphery
- Pulmonary Embolism (PE)
- Deep Vein Thrombosis (DVT)
- Arterio-Venous Fistulas for hemodialysis
- Arterial Emboli
- Acute Myocardial Infarction
Thrombectomy procedures are being used in cases of3:

The global market size of peripheral - thrombectomy devices in 20165:
$825 million
(Peripheral vascular: $210 million; Cardiovascular: $615 million)
About
Triticum is developing a new generation clot retriever device for the treatment of acute ischemic stroke and occlusions in peripheral vessels
- The Triticum architecture is inspired by biological concepts
- Made of soft polymer, using micro-surfaces technology to engage with the clot's micro-structure
- This results in a robust but yet gentle and safe retrieval of the blood clot
Team

Doron Ben Ami, MHA
Founder and Managing Director
Seasoned executive with more than 25 years of management experience holding various leadership roles.

Udi Sadeh, MD
Medical Director
Head of the Intervention Neuro-Radiology Stroke Service, Imaging Division, Sourasky Medical Center, Tel Aviv, Israel.

David F. Kallmes, MD
Scientific Advisor
Intervention Neuro-Radiology specialist at Mayo Clinic in Rochester, Minnesota, USA.

Oded Shoseyov, PhD
Scientific Advisor
A member of the Nano Science and Nano Technology Center at the Hebrew University of Jerusalem.

Lindsay D’Silva, PhD
Scientific Advisor
Post-Doctoral clinical research fellow for blood coagulation and developing novel blood biomarkers.

Christophe Cognard, MD
Scientific Advisor
Chairman of the Department of Diagnostic and Therapeutic Neuroradiology, at the University Hospitals Purpan and Rangueil of Toulouse, France. Previously

David Blossom, MJ
Commercial Advisor
Seasoned sales and marketing executive with more than 25 years of medical device experience.

Yuval Kahlon, D.Eng
Computational Design Advisor
Specialist in Design Computing. Experienced in implementing state-of-the-art technology for realizing complex geometry.

Nadav Ben Da’at, Eng, MBA
Director of Research & Development
Seasoned R&D executive with experience in the medical device industry development.

Doron Ben Ami, MHA
Founder and Managing Director
Seasoned executive with more than 25 years of management experience holding various leadership roles.

Udi Sadeh, MD
Medical Director
Head of the Intervention Neuro-Radiology Stroke Service, Imaging Division, Sourasky Medical Center, Tel Aviv, Israel.

David F. Kallmes, MD
Scientific Advisor
Intervention Neuro-Radiology specialist at Mayo Clinic in Rochester, Minnesota, USA.

Oded Shoseyov, PhD
Scientific Advisor
A member of the Nano Science and Nano Technology Center at the Hebrew University of Jerusalem.

Lindsay D’Silva, PhD
Scientific Advisor
Post-Doctoral clinical research fellow for blood coagulation and developing novel blood biomarkers.

Christophe Cognard, MD
Scientific Advisor
Chairman of the Department of Diagnostic and Therapeutic Neuroradiology, at the University Hospitals Purpan and Rangueil of Toulouse, France. Previously

David Blossom, MJ
Commercial Advisor
Seasoned sales and marketing executive with more than 25 years of medical device experience.

Yuval Kahlon, D.Eng
Computational Design Advisor
Specialist in Design Computing. Experienced in implementing state-of-the-art technology for realizing complex geometry.

Nadav Ben Da’at, Eng, MBA
Director of Research & Development
Seasoned R&D executive with experience in the medical device industry development.

Doron Ben Ami, MHA
Founder and Managing Director
Nadav Ben Da’at, Eng, MBA Director of Research & Development
Seasoned executive with more than 25 years of management experience holding various leadership roles. Among them Associate Vice President, Eastern Europe and Israel region at Merck, Managing Director of the Merck’s subsidiary in Israel and the General Manager of Lundbeck, Israel. Serves as a consultant for commercial and business development to Pharma and Medical Device companies.
Udi Sadeh, MD Medical Director

Udi Sadeh, MD
Medical Director
Doron Ben Ami, MHA Founder and Managing Director
Head of the Intervention Neuro-Radiology Stroke Service, Imaging Division, Sourasky Medical Center, Tel Aviv, Israel. A former pilot in the Israeli Air Force.
David F. Kallmes, MD Scientific Advisor

David F. Kallmes, MD
Scientific Advisor
Udi Sadeh, MD Medical Director
Intervention Neuro-Radiology specialist at Mayo Clinic in Rochester, Minnesota, USA. Head of the Applied Neuroradiology Laboratory that conducts multiple preclinical research and clinical trials for stroke and other related conditions. Working on establishing, developing and validating techniques and devices testing within the Intervention Neuro-Radiology field.
Oded Shoseyov, PhD Scientific Advisor

Oded Shoseyov, PhD
Scientific Advisor
David F. Kallmes, MD Scientific Advisor
A member of the Nano Science and Nano Technology Center at the Hebrew University of Jerusalem. He has extensive experience in Bio-Inspired Nanocomposite materials, has more than 160 publications and 50 patents and is the scientific founder of 10 biotech companies.
Lindsay D’Silva, PhD Scientific Advisor

Lindsay D’Silva, PhD
Scientific Advisor
Oded Shoseyov, PhD Scientific Advisor
st-Doctoral clinical research fellow for blood coagulation and developing novel blood biomarkers. Experienced in multiple imaging modalities (Cardiac, Ultrasonography, Scanning Electron Microscopy, and Histology).
Active as Clinical and Regulatory specialist for bringing novel medical devices to the U.S and European Markets.
Christophe Cognard, MD Scientific Advisor

Christophe Cognard, MD
Scientific Advisor
Lindsay D’Silva, PhD Scientific Advisor
Chairman of the Department of Diagnostic and Therapeutic Neuroradiology, at the University Hospitals Purpan and Rangueil of Toulouse, France. Previously held the position of President of the ESMINT (European Society of Minimal Invasive Neurological Therapies).
David Blossom, MJ Commercial Advisor

David Blossom, MJ
Commercial Advisor
Christophe Cognard, MD Scientific Advisor
Seasoned sales and marketing executive with more than 25 years of medical device experience. Worked with several prestigious medical device companies among them Boston Scientific Corporation, Covidien/Aspect Medical Systems, Cappella Medical Systems and InspireMD.
Yuval Kahlon, D.Eng Computational Design Advisor

Yuval Kahlon, D.Eng
Computational Design Advisor
David Blossom, MJ Commercial Advisor
Specialist in Design Computing. Experienced in implementing state-of-the-art technology for realizing complex geometry - from large scale architectural designs to nanoscale devices. Assistant Professor of Engineering Science & Design at the Tokyo Institute of Technology, Japan.
Nadav Ben Da’at, Eng, MBA Director of Research & Development

Nadav Ben Da’at, Eng, MBA
Director of Research & Development
Yuval Kahlon, D.Eng Computational Design Advisor
Seasoned R&D executive with experience in the medical device industry development. Co-Established Nordson Medical R&D site in Israel and served as Sr. Technical Director.
Served as Jetprep R&D Manager from early stage to its acquisition by Cantel Medical Corporation.